英文名字 Anti-Anoctamin-1 (extracellular)
中文名称 Anoctamin-1 (胞外)抗体(50 ul)
供应商 Alomone
产品货号 ALO-ACL-011-50
产品报价 ¥5872/50ul
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产品新闻
背景资料 Ano1 (or TMEM16A, DOG1 and others) the first member to be identified was found to be a Ca2+-activated Cl- channel therefore other members are likely to also be Cl- channels. These channels are expressed in many different tissues: bronchiolar epithelial cells, pancreatic acinar cells, proximal kidney tubule epithelium, retina, dorsal root ganglia and submandibular gland1. In fact, Ano1 gained a lot of attention as its activation may serve as a therapeutic treatment for cystic fibrosis since it is also expressed in the airways6. These Ca2+-activated Cl- channels are believed to play a role in development as knock out of Ano1 in mice causes abnormal development of the trachea7. Ano2 (TMEM16B) has been shown to mediate Ca2+-activated Cl- current in olfactory epithelium and photoreceptor synapses
Although relatively newly discovered channels, they are being discovered in many medical indications. Ano1 has become a marker in gastrointestinal tumors as its expression is significantly upregulated in such tumors. Similarly, Ano1 is also highly expressed other carcinomas.
应用类型 经验证,该抗体可应用于WB
免疫原 Anoctamin-1 (胞外)抗体的免疫原肽段为(C)EYVKRKQRYEVDFNLE。此免疫原序列来源于679-694 位氨基酸残基,该序列来源于小鼠 Anoctamin-1 (Accession编号为Q8BHY3),第3胞外环。
来源宿主
反应性 反应性:大鼠
保存建议 艾美捷为您提供的Anoctamin-1 (胞外)抗体(50 ul)为室温运输,建议您收到产品后㧟20℃保存。
产品说明书
其他 Alomone成立于1989年,已经成为全世界科学家信赖的最全面的离子通道研究工具供应商。产品覆盖离子通道、G蛋白耦联受体和神经信号研究所需的一抗、小分子、蛋白质和多肽等。所有Alomone产品均进行了生物实验验证,以冻干粉形式提供,可确保产品生物活性和保质期。Alomone可提供多种包装规格,灵活方便。作为Alomone Labs在中国的区域总代理,艾美捷科技购乐彩票将为中国客户提供最全面的Alomone Labs产品以及客户订制化服务。

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