英文名字 Anti-Angiotensin-(1-7) Mas Receptor
中文名称 Angiotensin-(1-7) Mas 受体抗体(0.2 ml)
供应商 Alomone
产品货号 ALO-AAR-013-0.2
产品报价 ¥7600/0.2ml
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产品新闻
背景资料 The angiotensin-(1-7) Mas receptor is the recently identified receptor of the biologically active heptapeptide angiotensin-(1-7).Angiotensin (Ang)-(1-7) is a metabolite of the well known peptide hormone Angiotensin (Ang) II, a key component of the renin-angiotensin system (RAS) that has a central role in cardiovascular homeostasis.
Considerably interest in Ang-(1-7) and its receptor aroused in the last few years since it became apparent that it can counterbalance most of Ang II effects. Thus Ang-(1-7) has vasodilator and hypotensive effects as well as antiarrhythmic and cardioprotective roles.The Ang-(1-7) Mas receptor belongs to the 7-transmembrane domain, G protein-coupled receptor (GPCR) superfamily and was originally described as a protooncogene.Signaling via the Ang-(1-7) Mas receptor is still poorly elucidated however, evidence indicates that the receptor is coupled to a Gq/11 protein that activates phospholipase C (PLC).The Ang-(1-7) Mas receptor is expressed in several organs including heart, kidney, blood vessels, testis and brain. Studies with Ang-(1-7) Mas receptor knockout mice have demonstrated the key role of this receptor in cardiovascular regulation as well as in the regulation of learning and memory.
应用类型 经验证,该抗体可应用于IH、WB等实验应用,也可用于 IC、IFC、IP等实验。
免疫原 Angiotensin-(1-7) Mas 受体抗体的免疫原肽段为(C)KIRKNTWASHSSK。此免疫原序列来源于212-224 位氨基酸残基,该序列来源于大鼠Angiotensin-(1-7) Mas 受体 (Accession编号为P12526),第三胞内环。
来源宿主
反应性 反应性:人、 小鼠、 大鼠
保存建议 艾美捷为您提供的Angiotensin-(1-7) Mas 受体抗体(0.2 ml)为室温运输,建议您收到产品后㧟20℃保存。
产品说明书
其他 Alomone成立于1989年,已经成为全世界科学家信赖的最全面的离子通道研究工具供应商。产品覆盖离子通道、G蛋白耦联受体和神经信号研究所需的一抗、小分子、蛋白质和多肽等。所有Alomone产品均进行了生物实验验证,以冻干粉形式提供,可确保产品生物活性和保质期。Alomone可提供多种包装规格,灵活方便。作为Alomone Labs在中国的区域总代理,艾美捷科技购乐彩票将为中国客户提供最全面的Alomone Labs产品以及客户订制化服务。

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